輸血相關循環過載(Transfusion-Associated Circulatory Overload, TACO)是輸血造成的可能併發症，主因是由於輸注過多的血液或輸血過快引起肺水腫，通常發生在大量快速輸血的患者，發生率約1-8%2，嚴重時病人要入住ICU、機械通氣甚至會導致死亡。而預防TACO的方式主要仰賴醫療人員對病人輸血量與輸血速度的管控3，這在大量快速輸液時尤其會是挑戰。
Prevention of TACO requires a controlled rate of infusion
Philip Lanzkowsky, Chapter 31 – Supportive Care of Patients with Cancer, Manual of Pediatric Hematology and Oncology (Fifth Edition), Academic Press, 2011, Pages 857-920.
預防TACO發生必須要控管輸液的速率
輸血量以及輸血速率的控管
貝爾曼特輸液管理系統RI-2是一款以幫浦驅動的快速輸液、輸血加溫裝置，有別於壓力、重力型的輸液方式，幫浦的優勢在於能精準設定流速(2.5 – 750 mL/min)，並隨時依據病人狀態作調整。
此外，RI-2支援『Bolus』功能可設定一次性地定量快速輸注(100、200、500、1000mL)，避免持續性定速輸液時容易導致輸液過量的風險。
參考資料：
[1]. Barmparas G, Huang R, Lee WG, et al, Overtransfusion of packed red blood cells during massive transfusion activation: a potential quality metric for trauma resuscitation, Trauma Surgery & Acute Care Open 2022;7:e000896. doi: 10.1136/tsaco-2022-000896.
[2]. Murphy EL, Kwaan N, Looney MR, et al. Risk factors and outcomes in transfusion-associated circulatory overload. Am J Med. 2013;126(4):357.e29-357.e3.57E38. doi:10.1016/j.amjmed.2012.08.019
[3]. Klanderman, RB, Wijnberge, M, Bosboom, JJ, Roelofs, JJTH, de Korte, D, van Bruggen, R, et al. Differential effects of speed and volume on transfusion-associated circulatory overload: A randomized study in rats. Vox Sang. 2022; 117: 371– 378.
[4]. Philip Lanzkowsky, Chapter 31 – Supportive Care of Patients with Cancer, Manual of Pediatric Hematology and Oncology (Fifth Edition), Academic Press, 2011, Pages 857-920.
